Sulphonamides – Medicinal Chemistry III B. Pharma 6th Semester
Sulphonamides Historical Development • First effective chemotherapeutic agents that could be used systemically for the cure of bacterial infections in …
Quantitative Structure Activity Relationship (QSAR) – Medicinal Chemistry III B. Pharma 6th Semester
Quantitative Structure Activity Relationship • Change in physico-chemical properties will affect the ADME • QSAR approach help in deciding which …
Pro-drugs – Medicinal Chemistry III B. Pharma 6th Semester
Pro-drugs • Initially used by Albert • Is a pharmacologically inactive compound that is converted into an active drug by …
Macrolides – Medicinal Chemistry III B. Pharma 6th Semester
MACROLIDES Contents • Macrolides – Introduction • Chemistry of Macrolides • Over view of Mechanism of action and Resistance of …
Lincomycins & Polypeptides – Medicinal Chemistry III B. Pharma 6th Semester
Lincomycins & Polypeptides Contents • Mechanism of action of Lincomycins • Study of Individual Lincomycins • Structures of lincomycin and …
Molecular Docking & Pharmacophore Modelling – Medicinal Chemistry III B. Pharma 6th Semester
Molecular Docking & Pharmacophore Modelling Molecular Docking & Pharmacophore Modelling Pharmacophore modeling • Common features in a molecule: • Hydrogen …
Combinatorial Chemistry – Medicinal Chemistry III B. Pharma 6th Semester
Combinatorial Chemistry • Combinatorial and parallel synthesis have become established tools in drug discovery and drug development • Use of …
Applications of Computational tools in Drug Design & Discovery – Medicinal Chemistry III B. Pharma 6th Semester
Applications of Computational tools in Drug Design & Discovery Importance of CADD • Traditional drug discovery includes random screening, serendipitous …
Cephalosporins & Monobactams – Medicinal Chemistry III B. Pharma 6th Semester
β-lactam Antibiotics Cephalosporins & Monobactams Contents • Cephalosporins – Principal antibiotic components • Nomenclature of Cephalosporins • Structures of Cephalosporins …
β-lactam Antibiotics – Medicinal Chemistry III B. Pharma 6th Semester
β-lactam Antibiotics Contents • β-lactam antibiotics – penicillins – History • Structure and properties of penicillin • Structure and activity …