Pharmacodynamics
Content
•
Principles
of drug action
•
Mechanisms
involved in drug action
•
Enzyme
inhibition
•
Receptor
•
Structure
of G – Protein coupled receptor
•
Effector
pathways of GPCR
•
Ion
channel receptor, enzyme linked receptor
•
Receptors
regulating gene expression
•
Functions
of receptors
•
Synergism
and antagonism
Intended Learning Outcomes
At the
end of this lecture, student will be able to
• Explain
principles of drug action
• Explain
mechanisms involved in drug action
• Describe
enzyme inhibition process
• Describe
Receptor
• Describe
G – Protein coupled receptor
• Explain
effector pathways of GPCR
• Describe
ion channel receptor, enzyme linked receptor and receptors regulating gene expression
• Explain
the functions of receptors
• Differentiate
between synergism and antagonism
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