Pharmaceutics One Shot MCQs
Pharmaceutics One Shot MCQs
Pharmaceutics, the science of drug formulation, plays a crucial role in ensuring the safety, efficacy, and quality of medications. This pharmaceutics one shot mcqs, a set of over 100 multiple-choice questions (MCQs) with answers is provided. These MCQs test your knowledge of various pharmaceutics topics such as tablet defects, drug dissolution, flow types, viscosity measurement, filtration equipment, drying techniques, and cleanroom classifications. This combination of notes and MCQs is designed for exam preparation, allowing you to quickly grasp critical information and test your understanding efficiently.
Whether you’re preparing for exams, interviews, or simply brushing up on your pharmaceutics knowledge, these one-shot notes and MCQs provide a fast, reliable, and comprehensive resource.
Pharmaceutics 100+ MCQs with Answers:
According to HEPA filter classifications, what is the particle count for a Class 100 area?
a) 100 particles per cubic foot
b) 10,000 particles per cubic foot
c) 1,000 particles per cubic foot
d) 100,000 particles per cubic foot
Answer: a) 100 particles per cubic foot
According to USP standards, what is the allowed weight variation for tablets weighing more than 324 mg?
a) ±10%
b) ±7.5%
c) ±5%
d) ±3%
Answer: c) ±5%
Which type of pharmaceutical water is used within 24 hours or stored at ≤ 5°C or ≥ 80°C?
a) Sterile Water for Injection
b) Purified Water
c) Water for Injection (WFI)
d) Bacteriostatic Water for Injection
Answer: c) Water for Injection (WFI)
Which of the following is an example of Newtonian flow?
a) Natural gums
b) Titanium dioxide suspension
c) Water
d) Firm jellies
Answer: c) Water
What is the typical disintegration time for uncoated tablets?
a) 15 minutes
b) 30 minutes
c) 60 minutes
d) 3 hours
Answer: a) 15 minutes
Which of the following is an insoluble lubricant?
a) Magnesium Stearate
b) Sodium Benzoate
c) Sodium Lauryl Sulfate (SLS)
d) Boric Acid
Answer: a) Magnesium Stearate
Which of the following mixing equipment is used for low-viscosity liquids?
a) Paddle Mixer
b) Propeller Mixer
c) Turbine Mixer
d) Sigma Blade Mixer
Answer: b) Propeller Mixer
What is the method used to determine the viscosity of Newtonian fluids?
a) Cone and plate viscometer
b) Cup and bob viscometer
c) Falling sphere viscometer
d) Ostwald viscometer
Answer: d) Ostwald viscometer
Which type of dryer is typically used for tablet granules?
a) Tunnel Dryer
b) Fluidized Bed Dryer (FBD)
c) Vacuum Dryer
d) Freeze Dryer
Answer: b) Fluidized Bed Dryer (FBD)
What is the definition of the partition coefficient (P)?
a) The degree of a drug’s ionization
b) A measure of a drug’s solubility in water
c) A measure of a drug’s lipophilicity and ability to cross cell membranes
d) The degree of molecular dispersion in an emulsion
Answer: c) A measure of a drug’s lipophilicity and ability to cross cell membranes
What is the zeta potential used to describe?
a) Ion-dipole interaction
b) Electro-osmosis
c) Streaming potential
d) Electrophoresis
Answer: d) Electrophoresis
In tablet compression, what is a common cause of lamination?
a) High turret speed
b) Poor die finish
c) Deep concave punches
d) Insufficient binder
Answer: a) High turret speed
Which grade corresponds to a Class 100 environment for aseptic preparation and filling?
a) Grade A
b) Grade B
c) Grade C
d) Grade D
Answer: a) Grade A
Which method is typically used to determine particle size ranging from 50–1500 microns?
a) Microscopy
b) Sieving
c) Sedimentation
d) Conductivity
Answer: b) Sieving
What is the ideal range of Hausner’s ratio for good flowability of powders?
a) Less than 1.25
b) Between 1.25 and 1.5
c) Greater than 1.5
d) 1.0 to 2.0
Answer: a) Less than 1.25
Which binder belongs to the synthetic/semisynthetic polymer category?
a) Acacia
b) Ethyl Cellulose
c) Starch Paste
d) Tragacanth
Answer: b) Ethyl Cellulose
Which dryer is suitable for chemical powders and crude drugs?
a) Fluidized Bed Dryer (FBD)
b) Tray Dryer
c) Rotary Dryer
d) Tunnel Dryer
Answer: b) Tray Dryer
Which phenomenon describes a gel turning into a sol upon agitation?
a) Rheopexy
b) Thixotropy
c) Dilatant Flow
d) Plastic Flow
Answer: b) Thixotropy
What is the permissible particle size for a HEPA filter?
a) Larger than 0.3 microns
b) Smaller than 0.5 microns
c) Larger than 1 micron
d) Smaller than 0.3 microns
Answer: a) Larger than 0.3 microns
What is the key application of the ICH stability zone IVb?
a) Hot/humid climates with higher humidity conditions
b) Cold storage for dry zones
c) Mediterranean climates
d) Tropical regions with low humidity
Answer: a) Hot/humid climates with higher humidity conditions
Which drying equipment is ideal for thermo-sensitive substances?
a) Tray Dryer
b) Vacuum Pan
c) Fluidized Bed Dryer (FBD)
d) Tunnel Dryer
Answer: b) Vacuum Pan
What type of solution does a liniment represent?
a) Aqueous solution
b) Alcoholic oily solution
c) Suspension
d) Gel
Answer: b) Alcoholic oily solution
Which classification corresponds to a high permeability and high solubility drug in the Biopharmaceutical Classification System (BCS)?
a) Class I
b) Class II
c) Class III
d) Class IV
Answer: a) Class I
Which filtration equipment is commonly used for insulin filtration?
a) Seitz Filter
b) Metal Filter (Edge Filter)
c) Membrane Filter
d) HEPA Filter
Answer: b) Metal Filter (Edge Filter)
Which method of sterilization is referred to as “cold sterilization”?
a) Bacteria-proof filters
b) Dry heat sterilization
c) Autoclaving
d) Radiation sterilization
Answer: a) Bacteria-proof filters
Which of the following is a deliquescent substance?
a) Caffeine
b) Codeine
c) Ephedrine
d) Cocaine
Answer: c) Ephedrine
What is the normal disintegration time for a hard gelatin capsule?
a) 15 minutes
b) 30 minutes
c) 45 minutes
d) 60 minutes
Answer: b) 30 minutes
Which of the following is a remedy for tablet sticking during compression?
a) Increase binder amount
b) Dry granules thoroughly
c) Use deep concave punches
d) Increase moisture content
Answer: b) Dry granules thoroughly
What is a common use of centrifugal force in pharmaceutical operations?
a) Sieving
b) Drying granules
c) Particle size separation
d) Sterilization
Answer: c) Particle size separation
Which term represents substances that lose water and become anhydrous?
a) Hygroscopic
b) Deliquescent
c) Efflorescent
d) Humectant
Answer: c) Efflorescent
Which of the following is used to measure flowability in powders?
a) Hausner’s Ratio
b) Zeta potential
c) Angle of Repose
d) Stokes’ Law
Answer: a) Hausner’s Ratio
Which type of tablet defect involves local detachment of the film?
a) Picking
b) Blistering
c) Capping
d) Pitting
Answer: b) Blistering
What is a significant cause of capping in tablets?
a) Poor die finish
b) Over-compression
c) Moist granules
d) Excessive lubrication
Answer: a) Poor die finish
Which of the following solvents is commonly used for determining partition coefficients?
a) Chloroform
b) Water
c) Glycerin
d) Ethanol
Answer: a) Chloroform
What is the purpose of a planetary motion mixer in the pharmaceutical industry?
a) Mixing viscous materials
b) Drying powders
c) Granulating solid mixtures
d) Filtering solutions
Answer: a) Mixing viscous materials
Which type of drug has a partition coefficient (P) greater than 1?
a) Hydrophilic drug
b) Lipophilic drug
c) Amphiphilic drug
d) Ionic drug
Answer: b) Lipophilic drug
Which dryer equipment is best suited for a batch process for paste or sludges?
a) Rotary Dryer
b) Vacuum Dryer
c) Tunnel Dryer
d) Freeze Dryer
Answer: b) Vacuum Dryer
What is the typical concentration range for Sodium Lauryl Sulfate (SLS) used as a soluble lubricant?
a) 0.1–0.5%
b) 1–5%
c) 10–15%
d) 0.01–0.1%
Answer: b) 1–5%
What is the acceptable time frame for using non-sterile Water for Injection (WFI)?
a) 12 hours
b) 24 hours
c) 48 hours
d) 72 hours
Answer: b) 24 hours
Which type of flow is exhibited by solutions like natural gums (e.g., CMC, sodium alginate)?
a) Newtonian Flow
b) Plastic Flow
c) Pseudoplastic Flow
d) Dilatant Flow
Answer: c) Pseudoplastic Flow
Which environmental grade corresponds to Class 1000 for aseptic processing?
a) Grade A
b) Grade B
c) Grade C
d) Grade D
Answer: b) Grade B
In a shake-flask method, the partition coefficient of a unionized drug is the ratio of its concentration in:
a) Aqueous and solid phases
b) Organic and aqueous phases
c) Solid and organic phases
d) Gaseous and liquid phases
Answer: b) Organic and aqueous phases
Which mixer is most suitable for free-flowing materials with uniform size and density?
a) Ribbon Blender
b) Paddle Mixer
c) Sigma Blade Mixer
d) Turbine Mixer
Answer: a) Ribbon Blender
Which of the following factors contributes to tablet chipping during compression?
a) Worn groove of the die
b) Over-lubrication
c) High moisture content
d) Excessive compression force
Answer: a) Worn groove of the die
Which term refers to the movement of liquid relative to a stationary solid under the influence of an electric field?
a) Electrophoresis
b) Zeta Potential
c) Electro-osmosis
d) Streaming Potential
Answer: c) Electro-osmosis
Which method of particle size determination involves the use of an Anderson pipette?
a) Sedimentation
b) Sieving
c) Microscopy
d) Conductivity
Answer: a) Sedimentation
What is the ideal method for determining the density of porous solids?
a) Bulk density method
b) Mercury displacement method
c) Helium pycnometer
d) Liquid displacement method
Answer: c) Helium pycnometer
Which of the following causes tablet cratering during coating?
a) High moisture content in granules
b) Temperature issues during coating
c) High compression pressure
d) Inadequate drying of the coating solution
Answer: d) Inadequate drying of the coating solution
Which instrument is used for determining particle size in the range of 0.5–500 microns by measuring equivalent volume?
a) Optical microscope
b) Sieving
c) Coulter counter
d) Centrifugal sedimentation
Answer: c) Coulter counter
Which drying process is typically used for drying paraffin wax, gelatin, and soap?
a) Tunnel Dryer (Belt/Conveyor Dryer)
b) Tray Dryer
c) Fluidized Bed Dryer
d) Freeze Dryer
Answer: a) Tunnel Dryer
Which of the following is an example of a natural binder used in tablet formulation?
a) Acacia
b) Polyvinyl Pyrrolidone (PVP)
c) Polyethylene Glycol (PEG)
d) Hydroxypropyl Methyl Cellulose (HPMC)
Answer: a) Acacia
Which term defines the ability of a substance to absorb moisture from the atmosphere and form a solution?
a) Efflorescent
b) Hygroscopic
c) Deliquescent
d) Absorbent
Answer: c) Deliquescent
Which tablet defect is caused by improper punch pressure or insufficient lubrication?
a) Picking
b) Pitting
c) Capping
d) Lamination
Answer: d) Lamination
What is the general function of a Z-blade mixer?
a) Drying granules
b) Filtration of solutions
c) Mixing viscous materials
d) Sieving powders
Answer: c) Mixing viscous materials
Which drying equipment is best suited for drying heat-sensitive substances at low temperatures?
a) Spray Dryer
b) Vacuum Dryer
c) Tray Dryer
d) Rotary Dryer
Answer: b) Vacuum Dryer
What concentration range of Avicel® is typically used as a disintegrant in tablet formulations?
a) 5-10%
b) 10-20%
c) 20-25%
d) 1-5%
Answer: b) 10-20%
Which of the following is an example of a rheopexic substance?
a) Petrolatum
b) Water
c) Magma gel
d) Bentonite clay
Answer: d) Bentonite clay
What is the primary function of the HEPA filter in pharmaceutical cleanrooms?
a) To remove water vapor
b) To control humidity levels
c) To remove airborne particles larger than 0.3 microns
d) To regulate temperature
Answer: c) To remove airborne particles larger than 0.3 microns
Which type of tablet coating defect occurs when a rough, non-glossy surface forms on the tablet?
a) Blistering
b) Blooming
c) Orange peel
d) Cratering
Answer: c) Orange peel
Which type of drying equipment is commonly used for drying solutions such as milk or coffee extract?
a) Tray Dryer
b) Spray Dryer
c) Freeze Dryer
d) Fluidized Bed Dryer
Answer: b) Spray Dryer
What is the role of sodium starch glycolate in tablet formulations?
a) Binder
b) Disintegrant
c) Lubricant
d) Coating agent
Answer: b) Disintegrant
What is the principle behind the diffusion layer model in drug dissolution?
a) Drug absorption rate is faster than dissolution
b) The rate-determining step is the solute diffusing from a saturated layer
c) The drug solubility is independent of particle size
d) Particle size increases dissolution rate
Answer: b) The rate-determining step is the solute diffusing from a saturated layer
Which tablet defect is characterized by the breaking or splitting of tablets at the edges during ejection?
a) Capping
b) Chipping
c) Cratering
d) Blistering
Answer: b) Chipping
What is the recommended disintegration time for enteric-coated tablets?
a) 15 minutes
b) 30 minutes
c) 60 minutes
d) 3 hours
Answer: d) 3 hours
Which method is used to determine particle size in the range of 5–10,000 microns?
a) Microscopy
b) Sieving
c) Sedimentation
d) Conductivity
Answer: b) Sieving
What is the ideal temperature range for storing Water for Injection (WFI)?
a) Below 10°C
b) Between 10°C and 25°C
c) Below 5°C or above 80°C
d) Room temperature
Answer: c) Below 5°C or above 80°C
Which powder flow characteristic is indicated by an angle of repose of more than 40 degrees?
a) Excellent flow
b) Passable flow
c) Good flow
d) Very poor flow
Answer: d) Very poor flow
What is the cause of tablet picking during compression?
a) Excessive lubrication
b) Rough or scratched punch faces
c) Low compression pressure
d) Over-dried granules
Answer: b) Rough or scratched punch faces
Which process involves the removal of moisture from substances by converting them directly from a solid to a gas phase?
a) Spray drying
b) Rotary drying
c) Freeze drying
d) Fluidized bed drying
Answer: c) Freeze drying
Which type of pharmaceutical water is sterile and used to reconstitute sterile solids?
a) Purified Water
b) Water for Injection (WFI)
c) Sterile Water for Injection
d) Bacteriostatic Water for Injection
Answer: c) Sterile Water for Injection
What is the common method for determining the viscosity of non-Newtonian fluids?
a) Falling sphere viscometer
b) Ostwald viscometer
c) Cone and plate viscometer
d) Microscopy
Answer: c) Cone and plate viscometer
Which class of environment corresponds to a Class 10000 for handling components after washing?
a) Grade A
b) Grade B
c) Grade C
d) Grade D
Answer: d) Grade D
What type of fluid exhibits an increase in viscosity when subjected to shear stress?
a) Newtonian
b) Pseudoplastic
c) Dilatant
d) Plastic
Answer: c) Dilatant
Which disintegrant works by swelling and is used in concentrations of 1-5%?
a) Alginic Acid
b) Starch
c) Polyplasdone®
d) Amberlite®
Answer: a) Alginic Acid
What is the concentration range of talc used as an insoluble lubricant in tablet formulations?
a) 0.25-1%
b) 1-2%
c) 2.5-5%
d) 5-10%
Answer: b) 1-2%
Which factor is not responsible for tablet capping?
a) High turret speed
b) Poorly finished dies
c) Incorrect ejection settings
d) Adequate lubrication
Answer: d) Adequate lubrication
Which piece of equipment is used for the continuous drying of granules and powders?
a) Freeze Dryer
b) Rotary Dryer
c) Fluidized Bed Dryer
d) Tray Dryer
Answer: b) Rotary Dryer
What is the most appropriate method for determining particle size in the range of 1–200 microns?
a) Microscopy
b) Sedimentation
c) Sieving
d) Conductivity
Answer: b) Sedimentation
What type of bond holds atoms together within molecules such as ionic and covalent bonds?
a) Intermolecular forces
b) Ion-dipole interaction
c) Intramolecular forces
d) Ion-induced dipole interaction
Answer: c) Intramolecular forces
Which tablet coating defect results in pits forming on the core without disrupting the coating film?
a) Pitting
b) Cratering
c) Picking
d) Blistering
Answer: a) Pitting
Which binder is most commonly used in tablet formulations and is derived from natural sources?
a) PVP (Polyvinyl Pyrrolidone)
b) Acacia
c) Sucrose
d) Tragacanth
Answer: b) Acacia
What is the recommended concentration range of Polyplasdone® as a disintegrant in tablets?
a) 1-5%
b) 5-10%
c) 10-15%
d) 0.5-5%
Answer: d) 0.5-5%
Which drying equipment is most suitable for drying granular solids using continuous process operations?
a) Tunnel Dryer
b) Tray Dryer
c) Rotary Dryer
d) Freeze Dryer
Answer: c) Rotary Dryer
What is the key factor responsible for eutectic mixture formation?
a) Components should have high solubility in water
b) Components should have miscibility in the solid state
c) Components should inhibit each other’s crystallization
d) Components should have high melting points
Answer: c) Components should inhibit each other’s crystallization
Which pharmaceutical water is used in single-dose containers for the reconstitution of sterile solids?
a) Purified Water
b) Sterile Water for Injection
c) Water for Injection (WFI)
d) Bacteriostatic Water for Injection
Answer: b) Sterile Water for Injection
What is the purpose of adjusting the sweep-off blade in tablet compression machines?
a) To reduce lamination
b) To ensure proper ejection of the tablets
c) To improve compression pressure
d) To reduce capping issues
Answer: b) To ensure proper ejection of the tablets
Which of the following describes a system where a drug’s in vitro dissolution rate correlates directly with in vivo absorption rate?
a) IVIVC Level A
b) IVIVC Level B
c) IVIVC Level C
d) Partition Coefficient System
Answer: a) IVIVC Level A
Which phenomenon describes the movement of dispersed charged particles under the influence of an electric field?
a) Electrophoresis
b) Electro-osmosis
c) Streaming potential
d) Sedimentation potential
Answer: a) Electrophoresis
What is the recommended drying time for tablet granules using a Fluidized Bed Dryer (FBD)?
a) 1 hour
b) 30 minutes
c) 2 hours
d) 15 minutes
Answer: b) 30 minutes
Which viscosity determination method is best for Newtonian fluids?
a) Cone and plate viscometer
b) Cup and bob viscometer
c) Ostwald viscometer
d) Capillary tube viscometer
Answer: c) Ostwald viscometer
Which of the following is classified as a hygroscopic and deliquescent substance?
a) Atropine
b) Ephedrine
c) Caffeine
d) Codeine
Answer: b) Ephedrine
What is a common cause of “picking” in tablet compression?
a) Rough punch faces
b) Improper lubrication
c) High compression pressure
d) Over-dried granules
Answer: a) Rough punch faces
Which equipment is used for separating blood plasma using sedimentation principles?
a) Filtration centrifuge
b) Sedimentation centrifuge
c) Ultracentrifuge
d) Angle centrifuge
Answer: b) Sedimentation centrifuge
In the Biopharmaceutical Classification System (BCS), drugs with low permeability and high solubility belong to which class?
a) Class I
b) Class II
c) Class III
d) Class IV
Answer: c) Class III
Which type of dryer is used for highly viscous materials or sludges?
a) Spray Dryer
b) Agitator Dryer
c) Freeze Dryer
d) Fluidized Bed Dryer
Answer: b) Agitator Dryer
What is the angle of repose for powders with excellent flowability?
a) Less than 25°
b) 25°-30°
c) 30°-40°
d) More than 40°
Answer: a) Less than 25°
Which method is used to measure the equivalent volume of particles in the 0.5–500 micron range?
a) Coulter Counter
b) Sieving
c) Microscopy
d) Sedimentation
Answer: a) Coulter Counter
Which type of equipment uses anchor-type paddles and is suitable for highly viscous materials?
a) Sigma Blade Mixer
b) Planetary Motion Mixer
c) Ribbon Blender
d) Propeller Mixer
Answer: b) Planetary Motion Mixer
Which tablet defect is characterized by the formation of pits on the tablet without disrupting the coating film?
a) Pitting
b) Cratering
c) Picking
d) Blooming
Answer: a) Pitting
Which factor is most likely to cause tablet lamination?
a) Excessive lubrication
b) High turret speed
c) Low compression pressure
d) Wet granules
Answer: b) High turret speed
What is the function of magnesium stearate in tablet formulations?
a) Binder
b) Disintegrant
c) Lubricant
d) Coating agent
Answer: c) Lubricant
Which piece of equipment is used for continuous drying of large quantities of powders and granular materials?
a) Fluidized Bed Dryer
b) Rotary Dryer
c) Tray Dryer
d) Vacuum Dryer
Answer: b) Rotary Dryer
Which of the following is an example of a film theory in drug dissolution?
a) Diffusion layer model
b) Hydrophobicity model
c) Partition coefficient model
d) Saturation model
Answer: a) Diffusion layer model
Which equipment is best suited for mixing high-viscosity ointments and creams?
a) Ribbon Blender
b) Sigma Blade Mixer
c) Propeller Mixer
d) Paddle Mixer
Answer: b) Sigma Blade Mixer
Which Latin term is used to indicate “immediately” on a prescription?
a) Statim (Stat.)
b) Sumat (Sum.)
c) Agit ante usum (Agit. a. us)
d) Dolore urgente (Dol. urg.)
Answer: a) Statim (Stat.)
What is the cause of tablet capping during the compression process?
a) Low turret speed
b) Over-compression of tablets
c) Poor die finish
d) Excessive binder usage
Answer: c) Poor die finish
Which drying equipment is used for freeze-drying heat-sensitive materials by sublimation?
a) Tray Dryer
b) Spray Dryer
c) Rotary Dryer
d) Freeze Dryer
Answer: d) Freeze Dryer
What type of flow occurs when viscosity decreases with increasing shear rate?
a) Newtonian Flow
b) Pseudoplastic Flow
c) Dilatant Flow
d) Plastic Flow
Answer: b) Pseudoplastic Flow
Which type of pharmaceutical water is pyrogen-free but not sterile?
a) Purified Water
b) Sterile Water for Injection
c) Water for Injection (WFI)
d) Bacteriostatic Water for Injection
Answer: c) Water for Injection (WFI)
Which method of tablet coating defect repair involves reducing the depth of bevels or dividing lines?
a) For cratering
b) For picking
c) For lamination
d) For capping
Answer: b) For picking
What is the main function of a cyclone separator in particle size separation?
a) Sieving particles based on size
b) Using centrifugal force to separate particles
c) Measuring particle density
d) Filtering solid particles
Answer: b) Using centrifugal force to separate particles
Which term describes the slow movement of liquid relative to a stationary solid when an electric field is applied?
a) Electro-osmosis
b) Electrophoresis
c) Streaming Potential
d) Sedimentation Potential
Answer: a) Electro-osmosis
Which type of tablet defect occurs when the film coating takes on a dull appearance due to temperature issues?
a) Cratering
b) Picking
c) Blooming
d) Orange peel
Answer: c) Blooming
Which of the following is a remedy for preventing sticking during tablet compression?
a) Increasing moisture content in the granules
b) Drying granules thoroughly
c) Decreasing the amount of binder
d) Increasing compression pressure
Answer: b) Drying granules thoroughly
What is the angle of repose for powders that exhibit poor flowability?
a) Less than 25°
b) 25° to 30°
c) 30° to 40°
d) More than 40°
Answer: d) More than 40°
Which of the following is considered a plastic (Bingham body) flow?
a) Water
b) Suspension of ZnO in mineral oil
c) Concentrated titanium dioxide suspension
d) Glycerine
Answer: b) Suspension of ZnO in mineral oil
Which type of mixing equipment is used for solid/powder mixing and works through shear and diffusion?
a) Propeller Mixer
b) Ribbon Blender
c) Turbine Mixer
d) Tumbling Mixer
Answer: d) Tumbling Mixer
What is the primary use of bacteriostatic water for injection?
a) It is used in single-dose containers
b) It is used for multi-dose containers
c) It is used to clean medical equipment
d) It is used for topical administration
Answer: b) It is used for multi-dose containers
Which formula is used to calculate pediatric doses based on a child’s age in years?
a) Cowling’s Formula
b) Fried’s Formula
c) Bastedo’s Formula
d) Clark’s Formula
Answer: a) Cowling’s Formula
Which classification does not belong to the Biopharmaceutical Classification System (BCS)?
a) Class I: High permeability, high solubility
b) Class II: High permeability, low solubility
c) Class III: Low permeability, high solubility
d) Class V: High permeability, no solubility
Answer: d) Class V: High permeability, no solubility
Which pharmaceutical environment grade is used for aseptic preparation and filling, corresponding to a Class 100 area?
a) Grade A
b) Grade B
c) Grade C
d) Grade D
Answer: a) Grade A
Which pharmaceutical process uses the Ostwald viscometer?
a) Viscosity determination of Newtonian fluids
b) Particle size determination
c) Drying of tablet granules
d) Mixing of powders
Answer: a) Viscosity determination of Newtonian fluids
What is the ideal granule density measurement method for porous solids?
a) Bulk density method
b) Mercury displacement method
c) Helium pycnometer
d) Liquid displacement method
Answer: c) Helium pycnometer
Which of the following is an insoluble lubricant that prolongs tablet disintegration?
a) Sodium Lauryl Sulfate
b) Magnesium Stearate
c) Boric Acid
d) Sodium Benzoate
Answer: b) Magnesium Stearate
Which mixing equipment is ideal for emulsification processes involving high-viscosity liquids?
a) Paddle Mixer
b) Propeller Mixer
c) Turbine Mixer
d) Sigma Blade Mixer
Answer: c) Turbine Mixer
Which tablet coating defect involves the formation of craters on the tablet core?
a) Cratering
b) Pitting
c) Picking
d) Blistering
Answer: a) Cratering
What is the most common solvent used in the shake-flask method for determining partition coefficient?
a) Water
b) Ethanol
c) Chloroform
d) Glycerin
Answer: c) Chloroform
Which drying equipment uses a belt or conveyor for the continuous drying of materials like gelatin or soap?
a) Tray Dryer
b) Rotary Dryer
c) Tunnel Dryer
d) Fluidized Bed Dryer
Answer: c) Tunnel Dryer
What is the concentration range of Sodium Lauryl Sulfate (SLS) when used as a soluble lubricant in tablet formulations?
a) 0.25-1%
b) 1-5%
c) 5-10%
d) 10-20%
Answer: b) 1-5%
Which method is commonly used to separate large quantities of powders based on particle size using gravity or air flow?
a) Sieving
b) Sedimentation
c) Elutriation
d) Microscopy
Answer: c) Elutriation
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