SOP on Cleaning of Dry Syrup Filling Machine

on Cleaning of Dry Syrup Filling Machine



Objective : To describe a cleaning procedure for the dry syrup filling machine.


Scope : To ensure that
the equipment is clean and free from any starting materials of previous batch
or product residues.


Responsibility : 1.It  is the responsibility of
operating staff to clean the equipment.

2. Production Chemist to ensure that
procedure is followed.


Materials &
Equipment :

Cleaning agent: Teepol or liquid soap.

Mops / brush / lint free cloth




Remove visible material from the machine with the
help of a jet of compressed air.

Dismantle the hopper, nozzle etc. and place in a
plastic tub.

Take the dismantled parts to washing area and clean
them with 10 liters of boiled tap water and drain the washings.

Prepare a Teepol solution (10ml à 10 liters water)
or liquid soap (50gm
à 5 liters water) and clean the surfaces of all the dismantled parts by

Wash all the dismantled parts by running tap water
for 5 minutes.

Wash all the dismantled parts with 5 liters of
purified water.

Finally rinse all the parts with previously boiled
purified water and drain it completely.

Send the wash water for analysis of residual active
ingredients of previous product.

Let all the machine parts dry in air or dry with a
clean lint free cloth, reassemble in the reverse order of dismantling and put a
label “Clean” or “Ready for use”.


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