SOP on Cleaning of Manual Capsule Filling Machine

on Cleaning of Manual Capsule Filling Machine



Objective : To describe cleaning procedure for Manual
Capsule Filling Machine.



To ensure that the equipment is clean and free from any starting materials
of  previous batch or product residues.


Responsibility : 1.It 
is the responsibility of operating staff to clean the equipment.

2. Production
Chemist to ensure that procedure is followed.


& Equipment :

Cleaning agent: Teepol or liquid soap.

Mops / brush / lint free cloth / Vacuum cleaner

Plastic / SS tub




At the end of day or product changeover remove any
visible material from the machine with the help of a nylon brush, vacuum
cleaner and jet of compressed air.

Dismantle the capsule filling plate and pin plate
from the unit.

Keep all dismantled parts in a plastic / SS tub
containing warm tap water.

Remove any visible material from surfaces of all
dismantled parts with the help of nylon brush or scrubber and drain the

Prepare a Teepol solution (10ml à 10 liters water)
or liquid-soap (50gm
à 5 liters water) and clean surfaces of dismantled parts by mopping.

Wash all dismantled parts with running tap water for
10 minutes and drain the washings. Repeat the procedure for another 5 minutes
and again drain the washings.

Finally rinse all dismantled parts with purified
water and drain it completely.

Send the wash water for analysis of residual active
ingredients of previous product.

   Let all the
parts dry in air or dry with a clean lint free cloth.

Re-assemble all cleaned parts in the reverse order
of dismantling and put a label “Clean” or “Ready for use”.



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