Size Separation
Contents of this
session
• Introduction to size separation
• Objectives and applications of size separation
• Size separation techniques
• Sedimentation and Elutriation techniques
• Bag filter, Air separator & Cyclone separator
Learning objectives
At the end of this PDF lecture student will be able to:
• Explain the various techniques of size separation
• Discuss the applications of size separation in
pharmaceutical formulations
• Explain the Andreasen’s technique of size separation
• Recommend the suitability of sedimentation or elutriation
method of size separation
• Discuss the principle in the size separation process of
particles using bag filters
Summary
• Size separation is an unit operation that involves the
separation of a mixture of various sizes of particles into two or more portions
by means of screening surface
• Types of separation includes diffusional and mechanical
separation
• Sieve number can be defined as the number of meshes
present in a linear length of 2.54 cm
• Centrifugal force is used to separate the solids from
fluids. The separation depends not only on the particle size but also on the
density of particles
• Bag filters are used for removing fines, which cannot be
separated by other methods
• In sedimentation technique, the particles move towards the
gravitational force and vice-versa in Elutriation technique
