Analeptics

Analeptics

The drug which increase the activity of various subunit or parts
of CNS (brain and spinal cord) are called CNS stimulant.

in CNS there are collection of cell which perform certain definite
function are called as an center .e.g. respiratory center, vomiting center,
heat regulating center, appetite controlling center.

Some type of drugs show mild CNS stimulant effect and produce
toxic side effect in slight higher dose e.g. strychnine.

Other type of drug show mild CNS. stimulant effect as a side
effect. e.g. Local Anesthetics (cocaine)

Sympathomimetics (dexamphetamine), Parasympatholytic (atropine)

CNS stimulant mainly used as an 1) Analeptics 2) Respiratory
stimulant

They are also useful to increase mental alertness and produce wakefulness
conditions.

To control appetite through CNS stimulant effect.

CNS stimulants Classification

CNS
stimulants can be classified as

1)  
Naturally
occurring drugs

a)  
Alkaloids
:

i) Xanthine derivatives – Caffeine,
Theophylline, Theobromin

ii) Other alkaloids –Strychnine, Lobeline

2) Synthetic drugs –Nikethamide,
Picrotoxin

3) Miscellaneous drugs – Cocaine (local
Anesthetics), Dexamphetamine (Sympathomimetics), Atropine
(Anticholinergics)  

Analeptics are CNS stimulants which
are used to reduce narcosis produced by CNS depression.

These drugs also act as respiratory
stimulants and thus are used to counteract drugs –induced Respiratory
Depression.

Caffeine

Structure of Caffeine: