• Tropical diseases caused by parasitic
worms (multicellular organism) which infest the body are called as helminth.
• The three main families of worms that
infest human being belong to two phyla.
1. Nematodes /nemathelminthes (round worm)
i) Cestodes (tape worm )
• Most of the
people carry one or another type of parasite in intestine .among the nematodes,
hook worm causes dangerous infestation as they remains attached to wall of
intestine and suck the blood.
infection are following
i) Safaris (round worm)
iii) Whip worm
iv) Guinea worm
v) Pin worm
• Cestodes are
unpleasant but do not cause serious illness.
Trematodes infestations contributing to death is Schistomiasis (blood flukes or
bilharzias) is when penetrating the unbroken skin to veins and causing slow
destruction of liver and kidney.
• This parasite
cause abdominal pain, anorexia, diarrhea with blood and mucus, enlarged liver
Definition: – Anthelmentics are the drugs which are used to combat (appose) any type of
helminthiasis (Helmenthic infections)
Classification of Anthelmentics:-
phenol and biphenyl:-e.g. Bithinol
3. Dyes: – Gentian
and related compound:-e.g. Piperazine citrate, DEC.
heterocyclic ring containing compound:-E.g.Mebendazole, (benzimidazole) niridazole
compound:-e.g. –Antimony Potassium Tartarate
Structure of Piperazine: