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Wolff-Kishner Reduction

Session Objectives

By the end of this
session, students will be able to:

• Wolff-Kishner Reduction

• Mechanism of Wolff-Kishner Reduction

Wolff-Kishner Reduction:

• The Wolff–Kishner
reduction is a reaction used in organic chemistry to convert carbonyl
functionalities into methylene groups.

• Reported
by Nikolai Kischner in 1911 and Ludwig Wolff in 1912

• It has
been applied to the total synthesis of scopadulcic acid B