The time interval between placing the order for purchase and receipt of items is called lead time. It represents how long it takes for an order to be fulfilled from the time the order is placed until the estimated data of receipt.

A humectant is a common moisturizing agent found in lotions, shampoos, and other beauty products used for our hair and skin. These are also used in many products including food, cosmetics, medicines and pesticides. It comes in three main forms: natural or unchanged, naturally derived, and synthetic.
• All humectants bind with water but some of them have an additional role. Some humectants first break down the dead skin cells clogging up our skin's surface.

Dose calculation for a child if his weight in pounds (lb) is known, can be done by Clark's rule
Child's dose = Body weight (lb)/150 X adult dose
= 50/150 x 20
= 1000/150
= 6.6 mg

As per GMP permitted limit of soluble content in water for injection is 10 ppm.
• Water is the most common aqueous vehicle used in pharmaceuticals. Several types of water are used in the preparation of drug product such as Nonpotable water, portable water, purified water for injection, sterile water for injection, Bacterio static WFI, sterile water for inhalation , etc.
• Water for Injection is a solvent used in the production of prarenteral and other preparations where products endotoxin content must be controlled, and in other pharmaceutical applications WFI is sterile, non pyrogenic, distailled water for the preparation of products for parenteral use. The WFI monograph also allows it to be packed in bulk for commercial use.

Secondary sources of drug information refer to indexing and abstracting systems that organize and provide easy retrieval of primary resources drug information sources have been traditionally classified in three categories primary, secondary and tertiary. Primary sources of drug information include unpublished studies. Tertiary sources of drug information summarize data from the primary literature and they include reference books, drug compendia and essential drugs list etc.

Sterilization :- It is the removal of all forms of microorganisms from the surface of an object. It includes both vegetative and spore forms
• Sterilization is classified into two types - physical and chemical sterilization -
• Physical sterilization includes heat sterilization it is done by two methods: Moist heat sterilization & Dry heat sterilization, Filtration, Irradiation (Non-ionizing radiation & Ionizing radiation), sound waves vibration, Fractional sterilization.
• Chemical sterilization are two types : gaseous and liquid.
• Moist Heat sterilization is one of the best methods of sterilization. It is done with the help of an instrument called an autoclave. An autoclave works on the principle of producing steam under pressure. Thus moist heat sterilization is also known as stem sterilization.
• Some micro-organisms resistant to moist heat sterilization
• Bacillus subtilis variety 5230.
• Bacillus stearothermophilus.
• Clostridium sporogenes.
Note:- The commission has accepted option (c) only correct answer to this question.

In a prescription the Latin term 'Dolore Urgents' signifies that it is to be taken when the pain is severe.

The abbreviation for b.i.d is bis in die which in Latin means twice a day, and oculent is the term for eye medicine. Therefore, Oculent. Ciprofloxacin 0.3% b.i.d represents the pharmacist's instruction as twice a day on the eyes.

In dry powder inhalers, material like Leucine is made to modify adhesive properties between drug and carrier particles. Leucine actually has multiple purposes as it inhances the dispensability and aerosolization of particles, and hence increase their emitted dose and fine particle fraction (FPF).

In the ABC analysis, 'A' items are those goods or drugs having the highest annual consumption value approximately 70 to 80% but also they are relatively small (about 10 to 20%) in numbers.

Codification is the process of assigning a number or symbol to each store item, along with a name, in order to make it easy and convenient to identify. It cannot yet eliminate the chances of duplication of items because a duplicate item can easily be placed with a same code given to original item.

Fluid thioglycolate media is used for the detection of both aerobes and anaerobes. In the fluid thioglycolate solution it has been found that aerobes grow at upper surface as they requires oxygen and on the other hand anaerobes grow at the bottom of the solution because they can grow without oxygen.

In ABC analysis, the A items are 10% - 20% of items and 70% - 80% of their expenditure. This means that a items comprise a relatively small number of items but have a relatively high consumption.

The primary source of carbon, used in typical cell culture media is carbohydrate (or glucose). In this process some of the carbon turns in CO2 during respiration while providing energy to the cell metabolism.

The Carr's index is an indicator of the compressibility of a powder. It is named after the scientist Raph J. Carr, Jr. The Carr index is calculated by the formula

Fluid thioglycollate medium is the best way to determine whether bacteria are aerobic or anaerobic, i.e. when are grow these bacteria in a test tube filled with thioglycollate nutrient broth, it will be observed that anaerobic bacteria will grow at the bottom of the test tube i.e. away from oxygen, on the other hand aerobic bacteria will grow at the top of the test tube, nearest to the oxygen.

The glass containers used for pharmaceutical packaging, are made of Type-I glass, which is known as borosilicate glass, This type of glass has a high melting point to withstand high temperatures, it also has high hydrolytic resistance and it is resistant to chemical substances. Borosilicate glass (Type-I) is used for laboratory glass apparatus, water for injection and for parenteral and non-parenteral use.

The pharase Ad. Lib is a shortened form of the Latin Ad. libitum, which means at one's pleasure or as much as one likes.

Unit dose dispensing method is the drug distributing system, where medications ordered, packed, handled, administered and charged in multiples of singledose units containing a pre-determined amount of drugs.

The heart of the patient counseling session is the counseling content. During this step, it has been explained to the patient by a pharmacist about his or her medications and treatment regimens.

ABC is an important inventory control technique useful in determining how much to order. It classifies the inventory items based on the item's consumption values.

A Cargile membrane suture was prominently used in the beginning 20th century in abdominal surgery. It is made from the peritoneum of the Ox.

In the preparation of an ointment and in other pharmaceutical applications and in cosmetic industries, parabens (methyl paraben, propyl paraben) are widely used as preservatives. These compounds and their salts are used mainly for their antifungal and antibacterial properties.

Indian pharmacopoeia 2022 {I,P - 2022} Contains a total of 92 new monographs, including 60 chemicals 21 vitamins, minerals, amino acids, etc, 3 biotechnology-derived therapeutic products, 4- human-derived therapeutic products, 4- human vaccines, 2 blood and blood-related products, 2 herbs and herbal related products, and seven phytopharmaceutical ingredients.

The subscription contains specific directions for the pharmacist on how to compound the medication. It contains instructions for the pharmacist on how to produce a dose, this means that it is a section of prescription that specifies the number of dosage units and amount to be administered.

Gelatin is a protein made from animal collagen, usually from cows and pigs. It's commonly used to make capsules, cosmetics, ointments and foods. It is commonly utilized as a gelling agent.
• It was selected as encapsulating material because being commonly used as a food ingredient it possesses unique gelation properties and is commercially available at a low cost.

Martindale is an extra pharmacopeia and it named so, as it was originally produced by the William Martindale in 1883 and now published by the pharmaceutical society of Great Britain. It contains information on the drugs presently used in Great Britain.

When a bacteria get into a hypotonic medium, the bacterial cell starts swelling and expand until it burst finally and this kind of cell bursting is known as cytolysis.