SOP
on Cleaning of Mass Mixer
Objective : To describe cleaning procedure for mass mixer.
Scope
:
To ensure that the equipment is clean and free from any starting materials of
previous batch or product residues.
Responsibility : 1.It is the responsibility of
operating staff to clean the equipment.
2. Production Chemist to ensure that
procedure is followed.
Materials
& Equipment :
1.
Cleaning agent: Teepol or Liquid Soap.
2.
Mops / nylon brush / lint free cloth
3.
SS Jug
Procedure
1.
Fill the mass mixer with 30 liters of hot tap water
and run the mass mixer for 10 minutes.
2.
Remove any visible material from surfaces of mass
mixer, shaft and blades with the help of brush.
3.
Drain out the water by tilting the mass mixer and
with the help of a SS jug.
4.
Prepare a Teepol solution (10ml à 10 liters water)
or liquid-soap (50gm à 5 liters water) and clean the surfaces, shaft and blades with clean
cloth & brush.
5.
Wash the inner surfaces of the mass mixer by running
tap water for 5 minutes, drain the washings. Repeat the procedure for another 5
minutes & again drain the washings.
6.
Wash the inner surfaces of the mass mixer by using
30 liters of purified water for 10 minutes and drain the washings.
7.
Finally rinse the mass mixer with previously heated
purified water and drain it completely. Pour 5 liters of purified water in mass
mixer and run for 5 minutes.
8.
Send the wash water for analysis of residual active
materials of previous product.
9.
Let it air dry and cover the equipment and put a
label “Cleaned” or “Ready for use”.
Reason for Review: – Minor revision in format.