• Clotting and clotting factors
• Hemophilia A and Hemophilia B
end of the PDF Notes, the students will be able to
• Explain hemophilia
• Describe the pathophysiology and
clinical features of Hemophilia
• Describe the clinical features and
treatment of Haemophilia a and Haemophilia b
Vasoconstriction to reduce blood flow
plug formation (von willebrand factor binds damaged vessle and platelets)
Activation of clotting cascade with generation of fibrin clot formation
Fibrinlysis (clot breakdown)
the ingredients, called factors, act like a row of dominoes toppling against
each other to create a chain reaction.
If one of the factors is missing this chain reaction cannot proceed.